Imidacloprid and Moxidectin Drops (for cat)
Ingredients:
Imidacloprid, Moxidectin
Appearance:
Yellow to brown yellow liquid.
Pharmacological action:
Antiparasitic drug.
Pharmacodynamics: Imidacloprid is a new generation of chlorinated nicotine insecticides. It has a high affinity for postsynaptic nicotinic acetylcholine receptors in the central nervous system of insects, and can inhibit the activity of acetylcholine, leading to parasite paralysis and death. It is effective against adult fleas and young fleas at various stages, and also has a killing effect on young fleas in the environment. The mechanism of action of moxidectin is similar to that of abamectin and ivermectin, and it has a good killing effect on internal and external parasites, especially nematodes and arthropods. The release of butyric acid (GABA) increases its binding force to the postsynaptic receptor, and the chloride channel opens. Moxidectin also has selectivity and high affinity for glutamate-mediated chloride ion channels, thereby interfering with neuromuscular signal transmission, relaxing and paralyzing the parasites, leading to the death of the parasites. Inhibitory interneurons and excitatory motor neurons in nematodes are its sites of action, while in arthropods it is the neuromuscular junction. The combination of the two has a synergistic effect.
Pharmacokinetics: After the first administration, imidacloprid was rapidly distributed to the cat's body surface on the same day, and remained on the body surface during the administration interval. 1-2 days after administration, the plasma concentration of moxidectin in cats reaches the highest level, and it is distributed throughout the body within one month and is slowly metabolized and excreted.
Indications: For the prevention and treatment of internal and external parasitic infections in cats. Prevention and treatment of flea infestation (Ctenocephalic felis), treatment of ear
mite infestation (Itchy ear mite), treatment of gastrointestinal nematode infection (adults, immature adults and L4 larvae of Toxocara felis and Anticostomum angiformis) . And can be used as an adjuvant treatment of allergic dermatitis caused by fleas.
Usage and dosage: External use. One dose, cat, per 1kg body weight, 10mg imidacloprid, 1mg moxidectin, equivalent to 0.1ml of this product. During prophylaxis or treatment, it is recommended to administer once a month. To prevent licking, apply only to the skin on the back of the cat's head and neck.
Cat weight (kg) | Applicable product type | Specification (ml) | Imidacloprid (mg/kg body weight) | Moxidectin (mg/kg body weight) |
≤4kg | small cat drops | 0.4ml | not less than 10 | not less than 1 |
>4-8kg | big cat drops | 0.8ml | 10-20 | 1-2 |
>8kg | Reasonable combination of products of different specifications | |||
Side effect:
(1) In individual cases, this product may cause a local allergic reaction, causing transient itching, hair adhesion, erythema or vomiting. These symptoms disappear without treatment.
(2) After administration, if the animal licks the administration site, transient neurological symptoms may occasionally appear, such as excitement, tremor, ophthalmic symptoms (dilated pupils, pupillary reflexes, and nystagmus), abnormal breathing, salivation, and Symptoms such as vomiting; occasionally transient behavioral changes such as reluctance to exercise, excitement, and loss of appetite.
Precautions:
(1) Do not use on kittens under 9 weeks of age. Do not use on cats who are allergic to this product. Pregnant and lactating dogs should follow veterinary advice before use.
(2) Cats under 1kg must follow veterinary advice when using this product.
(3) It is necessary to prevent Collies, Old English Sheepdogs and related breeds from
licking this product by mouth.
(4) Sick cats and cats with weak physique should follow the advice of veterinarians when using it.
(5) This product should not be used for dogs.
(6) During the use of this product, do not allow the drug in the drug tube to contact the eyes and mouth of the administered animal or other animals. Prevent animals that have run out of medicine from licking each other. Do not touch or trim the hair until the medicine is dry.
(7) Occasional 1 or 2 exposure of cats to water during the administration period will not significantly affect the efficacy of the drug. However, cats frequently bathed with shampoo or soaked in water may affect the efficacy of the drug.
(8) Keep children out of contact with this product.
(9) Do not store above 30°C, and do not use beyond the label expiration date.
(10) People who are allergic to this product should not administer it.
(11) When administering the drug, the user should avoid contact with the skin, eyes and mouth of this product, and do not eat, drink or smoke; after the administration, the hands should be washed. If it accidentally splashes on the skin, wash it with soap and water immediately; if it accidentally splashes into the eyes, rinse it with water immediately. If symptoms do not improve, please consult a doctor with instructions.
(12) At present, there is no specific rescue medicine for this product; if swallowed by mistake, oral activated charcoal can help detoxification.
(13) The solvent in this product may contaminate materials such as leather, fabrics, plastics, and painted surfaces. Before the administration site is dry, prevent these materials from contacting the administration site.
(14) Do not let this product enter surface water.
(15) Unused drugs and packaging materials should be disposed of in a harmless manner according to local requirements.
Withdrawal period: None.
Specifications:
(1) 0.4ml: Imidacloprid 40mg+ Moxidectin 4mg
(2) 0.8ml: Imidacloprid 80mg + Moxidectin 8mg
Storage: Sealed, stored at room temperature.
Shelf life: 2 years.
