Product Information
Main Ingredients: Ivermectin
Description: This product is a yellowish-white to light brown powder.
Pharmacological Action: Ivermectin is a semi-synthetic macrolide antibiotic produced by the fermentation of the soil microorganism Streptomyces avermitilis. It is a broad-spectrum antiparasitic drug effective against internal and external parasites, particularly nematodes (roundworms) and arthropods, but ineffective against cestodes, trematodes, and protozoa. The mechanism of action may involve increasing the release of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in the parasite, thereby blocking nerve signal transmission, causing muscle cells to lose contraction ability, and leading to parasite death. The peripheral neurotransmitter in mammals is acetylcholine, which is not affected by ivermectin, and ivermectin does not easily cross the blood-brain barrier. Therefore, ivermectin premix has high safety for livestock.
The half-life of ivermectin in pigs is up to 4 days. The time to reach peak plasma concentration is 0.5 days after oral administration and 2 days after subcutaneous injection. However, the bioavailability after subcutaneous injection is much higher than oral administration; typically, the bioavailability after oral administration is only 41% of that after injection. After absorption, ivermectin is widely distributed in body tissues, with the highest concentration in the liver and adipose tissue. Ivermectin is usually oxidized into metabolites in the liver. Within 5 to 6 days, over 90% of ivermectin is excreted in feces, and only 0.5% to 2% is excreted in urine.
Indications: Used for the treatment of gastrointestinal nematodes, lungworms, sarcoptic mange mites, and hog lice in pigs.
Usage and Dosage: Calculated as ivermectin. Mixed feed: 2g per 1000kg feed, used continuously for 7 days.
Adverse Reactions: None
Precautions:
Add 2g of ivermectin per ton of feed, which is equivalent to adding 333g of this product per ton of finished feed, and mix thoroughly.
This product is for pigs only and cannot be used for pigs weighing over 100kg and other animals.
Operators should not eat or smoke when using this product and must wash hands after operation.
Keep this product out of reach of children.
Ivermectin is highly toxic to shrimp, fish, and aquatic organisms. Do not contaminate water sources with residual drug packaging.
Withdrawal Period: 7 days for finishing pigs under 100kg; 27 days for finishing pigs over 100kg.
Specification: 100g : 0.6g
Storage: Light protection, tightly closed, store in a cool and dry place.
Validity Period: 36 months.