Isoflurane

Description:

Isoflurane is a nonflammable, nonexplosive general inhalation anesthetic agent. Its chemical name is 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether, and its structural formula is:

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Each mL contains 99.9% isoflurane.

Indications:

Isoflurane is used for induction and maintenance of general anesthesia in dogs.

Contraindications:

Isoflurane is contraindicated in dogs with known sensitivity to isoflurane or to other halogenated agents.

Dosage and Administration:

Caution: Operating rooms should be provided with adequate ventilation to prevent the accumulation of anesthetic vapors.

Premedication: A premedication regimen, which may be employed depending upon the patient status, to avert excitement during induction, might include an anticholinergic, a tranquilizer, a muscle relaxant and a short-acting barbiturate.

Induction:

Dogs: Inspired concentrations of 2.0 to 2.5% isoflurane alone with oxygen following a barbiturate anesthetic induction are usually employed to induce surgical anesthesia in the dog.

These concentrations can be expected to produce surgical anesthesia in 5 to 10 minutes

Maintenance: The concentration of vapor necessary to maintain anesthesia is much less than that required to induce it

Dogs: Surgical levels of anesthesia in the dog may be sustained with a 1.5 to 1.8% concentration of isoflurane in oxygen.

The level of blood pressure during maintenance is an inverse function of isoflurane concentration

in the absence of other complicating problems. Excessive decreases, unless related to hypovolemia, may be due to depth of anesthesia and in such instances may be corrected by lightening the level of anesthesia.

Recovery from isoflurane anesthesia is typically uneventful.

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Storage: 

Keep container tightly closed & store in cool place and protected from light.

Packing: 100ml/Bottle

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